Product Type > Proteins

Recombinant Human TGF-beta 1/TGFB1 Protein (RP00451)

Datasheet

Overview

Product name Recombinant Human TGF-beta 1/TGFB1 Protein
Catalog No. RP00451
Description Recombinant Human TGF-beta 1/TGFB1 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ala279-Ser390) of human TGF-beta 1/TGFB1 (Accession #P01137).
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 50 mM Glycine 50 mM NaCl pH4.0.Contact us for customized product form or formulation.
Species Human
This protein belongs a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
Synonym TGFB1; CED; DPD1; LAP; TGFB; TGFbeta; transforming growth factor beta-1; TGF-beta 1; CED; DPD1; LAP; TGFB; TGFbeta; TGF-β
Expressed Host HEK293 cells
Tag No tag
Swiss-Prot P01137
Gene ID 7040
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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Antibodies (7)

Proteins (5)

* For research use only. Not for therapeutic or diagnostic purposes.

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