Product Type > Proteins

Recombinant Human GITR Protein (RP01116)

Datasheet

Overview

Product name Recombinant Human GITR Protein
Catalog No. RP01116
Description Recombinant Human GITR Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Gln26-Glu161) of human GITR (Accession #Q9Y5U5) fused with an Fc tag at the C-terminus.
Purity > 95% by SDS-PAGE.
Endotoxin < 1.0 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Species Human
This protein is a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Synonym TNFRSF18; AITR; CD357; GITR; GITR-D
Expressed Host Mammalian
Tag C-Fc
Swiss-Prot Q9Y5U5
Gene ID 8784
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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* For research use only. Not for therapeutic or diagnostic purposes.

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