Product Type > Proteins

Recombinant Human Dkk-3 Protein (RP00355)

Datasheet

Overview

Product name Recombinant Human Dkk-3 Protein
Catalog No. RP00355
Description Recombinant Human Dkk-3 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ala22-Ile350) of human Dkk-3 (Accession #Q9UBP4) fused with a 6×His tag at the C-terminus.
Bio-Activity Measured by its ability to inhibit proliferation of HeLa human cervical epithelial carcinoma cells. The ED50 for this effect is 3-12 μg/mL.
Purity > 95% by SDS-PAGE.
Endotoxin < 1 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.Contact us for customized product form or formulation.
Species Human
This protein belongs a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
Synonym DKK3; REIC; RIG; RIG; CRRL; REIC
Expressed Host HEK293 cells
Tag C-6×His
Swiss-Prot Q9UBP4
Gene ID 27122
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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Antibodies (4)

Proteins (1)

* For research use only. Not for therapeutic or diagnostic purposes.

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