Active Recombinant SARS-COV-2 Spike S1+S2 ECD(S-ECD) Protein (RP01260LQ)

Overview

Product name	Active Recombinant SARS-COV-2 Spike S1+S2 ECD(S-ECD) Protein
Catalog No.	RP01260LQ
Description	Active Recombinant SARS-COV-2 Spike S1+S2 ECD(S-ECD) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val11-Gln1208) of SARS-COV-2(2019-nCoV) S1+S2 ECD (S-ECD) (Accession #YP_009724390.1) fused with a 6×His tag at the C-terminus.
Bio-Activity	Measured by its binding ability in a functional ELISA. Immobilized Recombinant SARS-CoV-2 Spike S1+S2 ECD-His at 2 μg/mL (100 μL/well) can bind Recombinant Human ACE2 with a linear range of 0.15-9.92 ng/mL.
Purity	>97% by SDS-PAGE.
Endotoxin	< 0.1 EU/μg of the protein by LAL method.
Formulation	Supplied as a 0.22 μm filtered solution in PBS, pH 7.4.Contact us for customized product form or formulation.Contact us for customized product form or formulation.
Species	SARS-COV-2
Calculated MW	133.8kDa

The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates thisinteraction.The S protein plays key parts in the induction of neutralizing-antibody and T-cellresponses, as well as protective immunity.

Product information

Synonym	cov spike Protein; 2019-nCoV; ncov spike Protein; 2019-nCoV; coronavirus spike Protein; 2019-nCoV; S glycoprotein; COVID-19; S protein; Spike glycoprotein
Expressed Host	HEK293 cells
Tag	C-His
Gene ID	43740568

Usage guide

Storage	This product is stable at ≤ ‑70°C for up to 6 months from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.