Product Type > Antibodies > Primary Antibodies > Monoclonal Antibodies

c-Myc Mouse mAb (A11029)

Publications (5) Datasheet SDS

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Human, Mouse, Rat

ABclonal:Western blot - c-Myc Mouse mAb (A11029)

Western blot analysis of extracts of Jurkat cells, using MYC antibody (A11029).

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Overview

Product name c-Myc Mouse mAb
Catalog No. A11029
Host species Mouse
Purification method Affinity purification
Isotype IgG1, Kappa
CloneNo. AMC0489

Background

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.

Immunogen information

Immunogen A synthetic peptide of human MYC
Sequence Email for sequence
Gene ID 4609
Swiss prot P01106
Synonyms MRTL; MYCC; c-Myc; bHLHe39
Calculated MW 51kDa
Observed MW 60kDa

Applications

Reactivity Human, Mouse, Rat
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
  • WB 1:500 - 1:2000
  • IF/ICC 1:50 - 1:100
  • IP 1:20 - 1:50
Storage buffer Store at 4℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, pH7.3.
Application key Western blotting    Immunofluorescence    Immunoprecipitation    
Positive samples Jurkat
Cellular location Nucleus, nucleolus, nucleoplasm
Customer validation

IHC (Homo sapiens, Mus musculus)

WB (Homo sapiens, Mus musculus)

Research Area

c-Myc Mouse mAb images

ABclonal:Western blot - c-Myc Mouse mAb (A11029)}

Western blot - c-Myc Mouse mAb (A11029)

Western blot analysis of extracts of Jurkat cells, using MYC antibody (A11029).

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Related Targets

Based on existing publications, the following genes are closely related to research on MYC. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to MYC. (Distance between topics and target gene indicate popularity.) MYC

* Data provided by citexs.com, for reference only.

Publishing research using A11029? Please let us know so that we can cite the reference in this datasheet.

Antibodies (12)

ELISA Kits (1)

Secondary Antibodies (17)

* For research use only. Not for therapeutic or diagnostic purposes.

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