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Recombinant Human IL-13 Protein (RP01105)

Datasheet

Overview

Product nameRecombinant Human IL-13 Protein
Catalog No.RP01105
DescriptionRecombinant Human IL-13 Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Leu25-Asn146) of human IL-13 (Accession #P35225) fused with a 6×His tag at the C-terminus.
Purity> 95% by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.22 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
SpeciesHuman
This protein is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
SynonymInterleukin-13; IL-13;
Expressed HostMammalian
Tag6×His tag at the C-terminus
Swiss-ProP35225
Gene ID3596
StorageStore the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
ReconstitutionReconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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