Product Type > Antibodies > Primary Antibodies > Polyclonal Antibodies

PLEKHA1 Rabbit pAb (A16009)

Datasheet SDS

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Human

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Overview

Product name PLEKHA1 Rabbit pAb
Catalog No. A16009
Host species Rabbit
Purification method Affinity purification
Isotype IgG

Background

This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3, 4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

Immunogen information

Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 285-404 of human PLEKHA1 (NP_067635.2).
Sequence SGAIVAQRGPGRSASSEHPPGPSESKHAFRPTNAATATSHSTASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQTVSPREPASKVTEQALLRPQSKNGPQEKDCDLVDLDDASLPVSDV
Gene ID 59338
Swiss prot Q9HB21
Synonyms TAPP1; PLEKHA1
Calculated MW 46kDa
Observed MW

Applications

Reactivity Human
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application key
Positive samples
Cellular location Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein

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Related Targets

Based on existing publications, the following genes are closely related to research on PLEKHA1. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to PLEKHA1. (Distance between topics and target gene indicate popularity.) PLEKHA1

* Data provided by citexs.com, for reference only.

Publishing research using A16009? Please let us know so that we can cite the reference in this datasheet.

* For research use only. Not for therapeutic or diagnostic purposes.

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