Product Type > Antibodies > Primary Antibodies > Monoclonal Antibodies

[KO Validated] Fatty Acid Synthase (FASN) Rabbit mAb (A21853)

KO/KDValidated

Datasheet SDS

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Human

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Overview

Product name [KO Validated] Fatty Acid Synthase (FASN) Rabbit mAb
Catalog No. A21853
Host species Rabbit
Purification method Affinity purification
Isotype IgG

Background

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Immunogen information

Immunogen Recombinant protein of human Fatty Acid Synthase (FASN).
Sequence Email for sequence
Gene ID 2194
Swiss prot P49327
Synonyms FAS; OA-519; SDR27X1; N)
Calculated MW 273kDa
Observed MW Refer to figures

Applications

Reactivity Human
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
  • WB 1:500 - 1:2000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Application key Western blotting    
Positive samples
Cellular location Cytoplasm, Melanosome

Research Area

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Related Targets

Based on existing publications, the following genes are closely related to research on FASN. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to FASN. (Distance between topics and target gene indicate popularity.) FASN

* Data provided by citexs.com, for reference only.

Publishing research using A21853? Please let us know so that we can cite the reference in this datasheet.

Antibodies (6)

ELISA Kits (1)

Secondary Antibodies (23)

* For research use only. Not for therapeutic or diagnostic purposes.

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