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IL6 Rabbit pAb (A11114)

Review (1)Publications (2) Datasheet

ABclonal:Immunohistochemistry - IL6 Polyclonal Antibody (A11114)

Immunohistochemistry of paraffin-embedded rat brain using IL6 antibody (A11114) at dilution of 1:100 (40x lens).

ABclonal:Immunohistochemistry - IL6 Polyclonal Antibody (A11114)

Immunohistochemistry of paraffin-embedded human esophagus using IL6 antibody (A11114) at dilution of 1:100 (40x lens).

ABclonal:Immunohistochemistry - IL6 Polyclonal Antibody (A11114)

Immunohistochemistry of paraffin-embedded mouse stomach using IL6 antibody (A11114) at dilution of 1:100 (40x lens).

Review
ABclonal: review for IL6 Rabbit pAb(A11114)

Overview

Product nameIL6 Rabbit pAb
Catalog No.A11114
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 30-212 of human IL6 (NP_000591.1).
SequenceVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Gene ID3569
Swiss protP05231
SynonymsIL6; BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6
Calculated MW23kDa
Observed MW
ReactivityHuman, Mouse, Rat
Tested applicationsWBIHCICCIFIPChIPChIP-seqRIPFCELISAMeDIPNucleotide ArrayDBFACSCoIP
Recommended dilutionIHC 1:50 - 1:100
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application keyImmunohistochemistry    
Positive samples
Cellular locationSecreted
Customer validation

(Mouse breast cancer)

IHC(Mus musculus)

IF(Mus musculus)

ABclonal:Immunohistochemistry - IL6 Polyclonal Antibody (A11114) }

Immunohistochemistry - IL6 Polyclonal Antibody (A11114)

Immunohistochemistry of paraffin-embedded rat brain using IL6 antibody (A11114) at dilution of 1:100 (40x lens).
ABclonal:Immunohistochemistry - IL6 Polyclonal Antibody (A11114) }

Immunohistochemistry - IL6 Polyclonal Antibody (A11114)

Immunohistochemistry of paraffin-embedded human esophagus using IL6 antibody (A11114) at dilution of 1:100 (40x lens).
ABclonal:Immunohistochemistry - IL6 Polyclonal Antibody (A11114) }

Immunohistochemistry - IL6 Polyclonal Antibody (A11114)

Immunohistochemistry of paraffin-embedded mouse stomach using IL6 antibody (A11114) at dilution of 1:100 (40x lens).

* For research use only. Not for therapeutic or diagnostic purposes.

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