Catalog No:A6554
Host species:Rabbit
Purity:Affinity purification
ABclonal:Immunohistochemistry - CD68 antibody (A6554)
ABclonal:Immunohistochemistry - CD68 antibody (A6554)

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This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Immunogen information

ImmunogenRecombinant funsion protein containing a sequence corresponding to amino acids 22-319 of human CD68 (NP_001242.2).
Gene ID968
Swiss ProtP34810
SynonymsGP110; LAMP4; SCARD1
Calculated MW31kDa/34kDa/37kDa
Observed MWRefer to figures


ReactivityHuman, Mouse
Tested applicationsWB, IHC
Recommended DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
Storage BufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application keyWestern blotting    Immunohistochemistry    
Positive samples
Cellular LocationCell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein, Single-pass type I membrane protein
Customer Validation

IF (Mouse)

CD68 Polyclonal Antibody images

ABclonal:Immunohistochemistry - CD68 antibody (A6554)

Immunohistochemistry - CD68 antibody (A6554)

Immunohistochemistry of paraffin-embedded human liver injury using CD68 antibody (A6554) at dilution of 1:100 (40x lens).
ABclonal:Immunohistochemistry - CD68 antibody (A6554)

Immunohistochemistry - CD68 antibody (A6554)

Immunohistochemistry of paraffin-embedded human esophageal cancer using CD68 antibody (A6554) at dilution of 1:100 (40x lens).

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