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Acetyl-DNMT1-K1127/K1129/K1131/K1133 pAb (A5595)

Datasheet

Overview

Product nameAcetyl-DNMT1-K1127/K1129/K1131/K1133 pAb
Catalog No.A5595
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
ImmunogenA synthetic peptide of human DNMT1
SequenceEmail for sequence
Gene ID1786
Swiss protP26358
SynonymsADCADN; AIM; CXXC9; DNMT; HSN1E; m.HsaI; MCMT
Calculated MW144kDa/183kDa/184kDa
Observed MWRefer to figures
ReactivityHuman
Tested applicationsWBIHCICCIFIPChIPChIPseqRIPFC
Recommended dilutionWB 1:500 - 1:2000
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application keyWestern blotting    
Positive samples
Cellular locationNucleus

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