Product Type > Antibodies > Primary Antibodies > Acetyl-specific Antibodies

Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb (A5595)

Publication (1) Datasheet COA

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Human, Mouse, Rat

ABclonal:Immunofluorescence - Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb (A5595)

Immunofluorescence analysis of C6 cells using Acetyl-DNMT1-K1127/K1129/K1131/K1133 antibody (A5595) at dilution of 1:100. Blue: DAPI for nuclear staining.

You may also interested in:

Overview

Product name Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb
Catalog No. A5595
Host species Rabbit
Purification method Affinity purification
Isotype IgG

Background

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

Immunogen information

Immunogen A synthetic acetylated peptide around K1127 & K1129 & K1131 & K1133 of human DNMT1 (NP_001124295.1).
Sequence KGKGKGK
Gene ID 1786
Swiss prot P26358
Synonyms AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN; m.HsaI; Acetyl-DNMT1-K1127/K1129/K1131/K1133
Calculated MW 183kDa
Observed MW Refer to figures

Applications

Reactivity Human, Mouse, Rat
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
  • IHC-P 1:50 - 1:100
  • IF/ICC 1:50 - 1:100
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Application key Immunohistochemistry    Immunofluorescence    
Positive samples
Cellular location Nucleus
Customer validation

WB (Mus musculus)

Documents

Certificate of Compliance

To download a Certificate of Compliance, please enter your Lot number below:

Lot number

Research Area

Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb images

ABclonal:Immunofluorescence - Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb (A5595)}

Immunofluorescence - Acetyl-DNMT1-K1127/K1129/K1131/K1133 Rabbit pAb (A5595)

Immunofluorescence analysis of C6 cells using Acetyl-DNMT1-K1127/K1129/K1131/K1133 antibody (A5595) at dilution of 1:100. Blue: DAPI for nuclear staining.

Inquire About This Product

Submit your question about A5595 below and we will get back to you within one business day.

Alternatively, call us at 888.754.5670.

Related Targets

Based on existing publications, the following genes are closely related to research on DNMT1. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to DNMT1. (Distance between topics and target gene indicate popularity.) DNMT1

* Data provided by citexs.com, for reference only.

Publishing research using A5595? Please let us know so that we can cite the reference in this datasheet.

Antibodies (9)

ELISA Kits (1)

Secondary Antibodies (23)

* For research use only. Not for therapeutic or diagnostic purposes.

Select size and quantity
Contact us to order