Product name | Biotinylated Human IL-6 Monoclonal Antibody, Rabbit MAb(DET) |
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Catalog No. | RM17603 |
Catagory | Elisa Antibody Kit |
Application | ELISA |
Description | Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). |
Immunogen | E. coli-derived human IL-6 protein Pro29-Met212 Accession #Q75MH2 |
Purirty | Affinity purification |
Ig Type | Rabbit IgG |
Endotoxin Level | < 1.0 EU/μg of the protein by LAL method. |
Formulation | Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1, PH 7.4. |
CrossReactivity | Has no cross-reactivity in ELISA and WB with Recombinant human CNTF, IL-2 , IL-3, G-CSF, IL-4 , M-CSF, IL-5 , IL-1A, IL-1B , IL-6RA, IL-6RB, IL-7, IL-8&Recombinant mouse IL-6, IL-2, IL-4, IL-11, IL-12 |
Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Human IL-6 Sandwich Immunoassay
Recommended Concentration | Sample | |
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ELISA Capture | 1-4ug/mL | Human IL-6 Monoclonal Antibody, Rabbit MAb(CAP)(Cat. No. RM17601) |
ELISA Detection | 0.05-0.2ug/mL | Biotinylated Human IL-6 Monoclonal Antibody, Rabbit MAb(DET)(Cat. No. RM17603) |
Standard | 1.56-100pg/mL | Recombinant Human IL6 Protein(Cat. No. RP00201) |
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* For research use only. Not for therapeutic or diagnostic purposes.
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