Product Type > Proteins

Recombinant Human IgG1 Fc Protein (RP01124)

Datasheet

Overview

Product name Recombinant Human IgG1 Fc Protein
Catalog No. RP01124
Description Recombinant Human IgG1 Fc Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Asp104-Lys330) of human IgG1 Fc (Accession #P01857) fused with no tags.
Purity > 95% by SDS-PAGE.
Endotoxin < 1.0 EU/μg of the protein by LAL method.
Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Species Human
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity.
Synonym Human IgG; IGHG1; COB1; YAP; YAP2; YAP65; YKI; YAP1; human IgG (Fc)
Expressed Host Mammalian
Tag No tag
Swiss-Prot P01857
Gene ID 3500
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

Inquire About This Product

Submit your question about RP01124 below and we will get back to you within one business day.

Alternatively, call us at 888.754.5670.

* For research use only. Not for therapeutic or diagnostic purposes.

!OUT OF STOCK

See Below for Alternatives
Contact us to order