|Synonym||FH, FHC, LDL R, LDL Receptor, LDLCQ2|
|Protein Construction||High quality, high purity and low endotoxin recombinant Human LDLR / LDL Receptor Protein (His Tag) (10231-H08H), tested reactivity in Human and has been validated in SDS-PAGE.100% guaranteed.|
|Expressed Host||Human Cells|
|Shipping||In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.|
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
|Purity||> 85 % as determined by SDS-PAGE|
|Bio-Activity||Measure by its ability to bind with human PCSK9 in a functional ELISA . 1. Immobilized human PCSK9 at 10 μg/ml (100 μl/well) can bind biotinylated recombinant human LDLR . The EC50 of biotinylated human LDLR is 0.61 μg/ml. 2. Immobilized mouse PCSK9 at 10 μg/ml (100 μl/well) can bind biotinylated recombinant human LDLR . The EC50 of biotinylated human LDLR is 0.12 μg/ml .|
|Endotoxin||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N Terminal||Ala 22|
|Molecule Mass||The secreted recombinant human LDLR comprises 777 amino acids with a predicted molecular mass of 86 kDa. As a result of different glycosylation, it migarates with the apparent molecular mass of 110-140 kDa in SDS-PAGE under reducing conditions corresponding to the mature and immature form.|
|Storage||Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
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