Product Type > Antibodies > Primary Antibodies > Monoclonal Antibodies

Desmin Rabbit mAb (A10837)

Datasheet SDS COA

Tested applications: WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition

Reactivity:Human, Mouse, Rat

ABclonal:Western blot - Desmin Rabbit mAb (A10837)

Western blot analysis of various lysates using Desmin Rabbit mAb (A10837).
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

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Overview

Product name Desmin Rabbit mAb
Catalog No. A10837
Host species Rabbit
Purification method Affinity purification
Isotype IgG

Background

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Immunogen information

Immunogen Recombinant protein of human Desminmin
Sequence Email for sequence
Gene ID 1674
Swiss prot P17661
Synonyms CSM1; CSM2; CDCD3; LGMD1D; LGMD1E; LGMD2R; Desmin
Calculated MW 54kDa
Observed MW 53kDa

Applications

Reactivity Human, Mouse, Rat
Tested applications WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra) ELISA MeDIP Nucleotide Array DB FACS CoIP FCM CUT&Tag meRIP Inhibition
Recommended dilution
  • WB 1:10000 - 1:50000
  • IHC-P 1:50 - 1:200
  • IF/ICC 1:50 - 1:200
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application key Western blotting    Immunohistochemistry    Immunofluorescence    
Positive samples HT-1080, Mouse heart
Cellular location Cell membrane, Cytoplasm, sarcolemma

Documents

Certificate of Compliance

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Lot number

Research Area

Desmin Rabbit mAb images

ABclonal:Western blot - Desmin Rabbit mAb (A10837)}

Western blot - Desmin Rabbit mAb (A10837)

Western blot analysis of various lysates using Desmin Rabbit mAb (A10837).
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

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Related Targets

Based on existing publications, the following genes are closely related to research on DES. (Numbers indicate number of published articles where both targets appear.)

1/

Related Research Area

Based on existing publications, the following research topics are related to DES. (Distance between topics and target gene indicate popularity.) DES

* Data provided by citexs.com, for reference only.

Publishing research using A10837? Please let us know so that we can cite the reference in this datasheet.

Antibodies (4)

ELISA Kits (1)

Secondary Antibodies (23)

* For research use only. Not for therapeutic or diagnostic purposes.

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