Summary
Catalog No:A6554
Host species:Rabbit
Purity:Affinity purification
Isotype:IgG
ABclonal:Immunohistochemistry  - CD68 antibody (A6554)
ABclonal:Immunohistochemistry  - CD68 antibody (A6554)

To buy,select size,quantity

Background

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Immunogen information

ImmunogenRecombinant protein of human CD68
SequenceEmail for sequence
Gene ID968
Swiss ProtP34810
SynonymsGP110, LAMP4, SCARD1
Calculated MW31kDa/34kDa/37kDa
Observed MWRefer to Figures

Applications

ReactivityHuman, Mouse
Tested applicationsWB, IHC
Recommended DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
Storage BufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application keyWestern blotting    Immunohistochemistry    
Positive samples
Cellular LocationCell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein, Single-pass type I membrane protein
Customer Validation

IF (Mouse)

CD68 Polyclonal Antibody images

ABclonal:Immunohistochemistry  - CD68 antibody (A6554)

Immunohistochemistry - CD68 antibody (A6554)

Immunohistochemistry of paraffin-embedded human liver injury using CD68 antibody (A6554) at dilution of 1:100 (40x lens).
ABclonal:Immunohistochemistry  - CD68 antibody (A6554)

Immunohistochemistry - CD68 antibody (A6554)

Immunohistochemistry of paraffin-embedded human esophageal cancer using CD68 antibody (A6554) at dilution of 1:100 (40x lens).

Submit an review for A6554

  1. Please choose your application ,enter the information requested below. All fields are mandatory, except the ones marked as optional.
  2. When you're happy with the review, submit it by clicking on the Submit button.
1:  
H(s)     M(s)
H(s)      M(s)     Second(s)
(allowed file types: .jpg, .png, .tif, .bmp, .gif)
kDa

Reviews List

Ask Us About This Product

submit your question on A6554 below

During business hours, we will respond to your email with in 24 hours. For any questions submitted on the weekend, a response will be received on Monday.

For immediate assistance during business hours M-F (excluding major holidays), please contact us.

Publishing research using A6554? Please let us know so that we can cite the reference in this datasheet.

You Viewed