Summary
Catalog No:A14227
Host species:Rabbit
Purity:Affinity purification
Isotype:IgG
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Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Immunogen information

ImmunogenA synthetic acetylated peptide around K12 of human Histone H4 (NP_001029249.1).
SequenceGLGKG
Gene ID8366
Swiss ProtP62805
SynonymsH4/I, H4FI
Calculated MW11kDa
Observed MWRefer to Figures

Applications

ReactivityHuman, Mouse, Rat, Other (Wide Range)
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Storage BufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application keyWestern blotting    
Positive samples
Cellular LocationChromosome, Nucleus

Acetyl-Histone H4-K12 pAb images

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